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2,4-Dichloro-6-methoxy-1,3,5-triazine

  • CAS No.: 3638-04-8
  • Purity: 99%
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Manufacturer supply 2,4-Dichloro-6-methoxy-1,3,5-triazine 3638-04-8 with sufficient stock and high standard

  • Molecular Formula: C4H3Cl2N3O
  • Molecular Weight: 179.993
  • Appearance/Colour: WHITE POWDER OR CRYSTALS 
  • Vapor Pressure: 0.00022mmHg at 25°C 
  • Melting Point: 86-88 °C(lit.) 
  • Refractive Index: 1.545 
  • Boiling Point: 336.3 °C at 760 mmHg 
  • PKA: -1.40±0.10(Predicted) 
  • Flash Point: 157.2 °C 
  • PSA: 47.90000 
  • Density: 1.538 g/cm3 
  • LogP: 1.18700 

2,4-Dichloro-6-methoxy-1,3,5-triazine(Cas 3638-04-8) Usage

InChI:InChI=1/C4H3Cl2N3O/c1-10-4-8-2(5)7-3(6)9-4/h1H3

3638-04-8 Relevant articles

Synthesis and characterization of lanthanide complexes with a pentadentate triazine-based ligand

Pavelek, Lubomír,Ladányi, Vít,Ne?as, Marek,Moravec, Zdeněk,Wichterle, Kamil

, p. 134 - 141 (2016)

A series of mononuclear [Ln(L)(H2O)(NO3)...

Synthesis and antiproliferating activity of iron chelators of hydroxyamino-1,3,5-triazine family

Sun, Daekyu,Melman, Galina,LeTourneau, Nickolas J.,Hays, Allison M.,Melman, Artem

, p. 458 - 460 (2010)

We synthesized and evaluated new specifi...

Inhibition of acetolactate synthase isozyme II from Escherichia coli by a new azido-photoaffinity sulfonylurea

Ortega, Florence,Bastide, Jean

, p. 261 - 274 (1997)

The sulfonylurea herbicides are very pat...

Triazine based Mn (II) and Mn (II)/Ln (III) complexes: Synthesis, characterization and catecholase activities

Celik, Derya,Kose, Muhammet

, (2019)

In the current work, two triazine-based ...

A highly emissive fluorescent Zn-MOF: molecular decoding strategies for solvents and trace detection of dunnite in water

Das, Prasenjit,Mandal, Sanjay K.

, p. 21274 - 21279 (2018)

The strategic exploration of a highly em...

Two heptacoordinated manganese(II) complexes of giant pentadentate s-triazine bis-Schiff base ligand: Synthesis, crystal structure, biological and DFT studies

Soliman, Saied M.,El-Faham, Ayman,Elsilk, Sobhy E.,Farooq, Muhammad

, p. 275 - 285 (2018)

A new s-triazine bis-Schiff base chelati...

Synthesis of Amidation Agents and Their Reactivity in Condensation Reactions

Sole, Roberto,Agostinis, Lodovico,Conca, Silvia,Gatto, Vanessa,Bardella, Noemi,Morandini, Andrea,Buranello, Chiara,Beghetto, Valentina

supporting information, p. 1672 - 1682 (2021/02/01)

Nowadays, the development of new approac...

Synthesis and Antimicrobial Evaluation of Bis-morpholine Triazine Quaternary Ammonium Salts

Morandini, Andrea,Leonetti, Benedetta,Riello, Pietro,Sole, Roberto,Gatto, Vanessa,Caligiuri, Isabella,Rizzolio, Flavio,Beghetto, Valentina

supporting information, p. 3172 - 3176 (2021/08/03)

Efficient, environmentally and economica...

Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors

Russomanno, Pasquale,Assoni, Giulia,Amato, Jussara,D'Amore, Vincenzo Maria,Scaglia, Riccardo,Brancaccio, Diego,Pedrini, Martina,Polcaro, Giovanna,La Pietra, Valeria,Orlando, Paolo,Falzoni, Marianna,Cerofolini, Linda,Giuntini, Stefano,Fragai, Marco,Pagano, Bruno,Donati, Greta,Novellino, Ettore,Quintavalle, Cristina,Condorelli, Gerolama,Sabbatino, Francesco,Seneci, Pierfausto,Arosio, Daniela,Pepe, Stefano,Marinelli, Luciana

, p. 16020 - 16045 (2021/11/10)

The inhibition of the PD-1/PD-L1 axis by...

Synthesis and kinetic study of a series of chloro- and m-carboxypyridium triazinyl reactive dyes

Huang, Huei-Chin,Wu, Chun-Guey

, (2021/02/12)

Five monochloro-s-triazinyl reactive dye...

3638-04-8 Process route

methanol
67-56-1

methanol

1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

2,4-Dichloro-6-methoxy-1,3,5-triazine
3638-04-8

2,4-Dichloro-6-methoxy-1,3,5-triazine

Conditions
Conditions Yield
With sodium hydrogencarbonate; In water; at 0 ℃; for 2.5h;
98%
With sodium hydrogencarbonate; at 20 ℃; for 0.5h;
98%
With sodium hydrogencarbonate; at 25 ℃; for 0.5h;
98%
With sodium hydrogencarbonate; at 0 ℃; for 1h;
97%
With sodium hydrogencarbonate; at 0 ℃; for 1h;
97%
With sodium hydrogencarbonate; In water; at 20 - 30 ℃;
86.2%
With sodium hydrogencarbonate; In water; at 20 - 30 ℃;
86.2%
With sodium hydrogencarbonate; In water; at 20 - 30 ℃; for 0.5h;
86.2%
methanol; With sodium hydrogencarbonate; In water; at 20 ℃;
1,3,5-trichloro-2,4,6-triazine; In water; at 30 ℃; for 0.5h;
86.2%
With sodium hydrogencarbonate; In water; at 20 - 30 ℃;
86.2%
With sodium hydrogencarbonate; In water; at 20 - 30 ℃; for 0.5h;
86.2%
With sodium hydrogencarbonate; at 10 - 20 ℃; for 1h;
85%
With sodium hydrogencarbonate; In water; at 30 ℃; for 0.5h;
84%
With sodium hydrogencarbonate; In water; at 20 ℃; for 1h;
83%
With sodium hydrogencarbonate; at 0 - 20 ℃;
82%
With sodium hydrogencarbonate; at 0 - 20 ℃; for 2h;
82%
With sodium hydrogencarbonate; In water; at 0 - 20 ℃; for 0.5h;
80%
methanol; 1,3,5-trichloro-2,4,6-triazine; In water; acetone; for 0.333333h;
With potassium carbonate; In water; acetone; at 0 ℃; for 2h;
76.3%
With sodium hydrogencarbonate; at 0 ℃; for 0.333333h;
74%
With sodium hydrogencarbonate; at 0 ℃; for 0.333333h;
74%
With sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;
73%
With sodium hydrogencarbonate; In water; at 30 ℃;
67%
With sodium hydrogencarbonate; for 1h; Ambient temperature;
60%
With sodium hydrogencarbonate; at 0 - 10 ℃; for 1h;
57.8%
With sodium hydrogencarbonate; at 20 ℃;
55.1%
With sodium hydrogencarbonate; In water; at 0 - 20 ℃; for 0.5h;
50%
With 2,4,6-trimethyl-pyridine;
With sodium hydrogencarbonate;
With sodium hydrogencarbonate;
With ISOPROPYLAMIDE; In acetone; at 35 ℃; for 2.5h; Yield given;
With sodium hydrogencarbonate; at 20 ℃; for 0.5h;
With sodium hydrogencarbonate; at 30 ℃;
In water; at 0 - 10 ℃; pH=6;
With 2,6-dimethylpyridine; In acetone; at -2 - 20 ℃;
With sodium hydrogencarbonate; at 0 ℃; for 5h;
With sodium hydrogencarbonate; at 20 ℃; for 0.75h;
With sodium hydrogencarbonate; at 20 ℃; for 1h;
With sodium hydrogencarbonate; at 10 - 20 ℃; for 1h;
With sodium hydrogencarbonate; at 130 ℃; for 1h;
With sodium hydrogencarbonate; at 0 ℃;
With sodium hydrogencarbonate; at 0 ℃; for 10h;
With sodium hydrogencarbonate; In water; acetone; at 0 - 5 ℃;
With pyrrolidine; at 0 ℃; for 1h;
With sodium hydrogencarbonate;
With sodium hydrogencarbonate; at 10 - 25 ℃;
1,3,5-trichloro-2,4,6-triazine
108-77-0

1,3,5-trichloro-2,4,6-triazine

2,4-Dichloro-6-methoxy-1,3,5-triazine
3638-04-8

2,4-Dichloro-6-methoxy-1,3,5-triazine

Conditions
Conditions Yield
With sodium hydrogencarbonate; In methanol; (2S)-N-methyl-1-phenylpropan-2-amine hydrate;
With sodium hydrogencarbonate; In methanol; water;

3638-04-8 Upstream products

  • 67-56-1
    67-56-1

    methanol

  • 108-77-0
    108-77-0

    1,3,5-trichloro-2,4,6-triazine

  • 124-41-4
    124-41-4

    sodium methylate

  • 108-98-5
    108-98-5

    thiophenol

3638-04-8 Downstream products

  • 14925-07-6
    14925-07-6

    2,4-bis-aziridin-1-yl-6-methoxy-[1,3,5]triazine

  • 3140-73-6
    3140-73-6

    2-chloro-4,6-dimethoxy-1 ,3,5-triazine

  • 140452-00-2
    140452-00-2

    2,4-dibenzoyloxy-6-methoxy-1,3,5-triazine

  • 108718-58-7
    108718-58-7

    2-methoxy-4,6-diphenyl-1,3,5-triazine

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