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Factory Sells Best Quality HEXANOIC ANHYDRIDE 2051-49-2 with stock
- Molecular Formula: C12H22O3
- Molecular Weight: 214.305
- Appearance/Colour: clear colorless to light yellow liquid
- Vapor Pressure: 0.0263mmHg at 25°C
- Melting Point: -40 °C
- Refractive Index: n20/D 1.428(lit.)
- Boiling Point: 246.999 °C at 760 mmHg
- Flash Point: 116.614 °C
- PSA: 43.37000
- Density: 0.943 g/cm3
- LogP: 3.21680
HEXANOIC ANHYDRIDE(Cas 2051-49-2) Usage
|
Preparation |
To an ice-cooled flask containing 116 gm (1.0 mole) of n-caproic acid is added 21.0-23.10 gm (0.5-0.55 mole) of ketene at a rate of 0.45 mole/hr. The reaction mixture is fractionally distilled at atmospheric pressure to afford a forecut of acetone, acetic acid, and acetic anhydride. The oil bath is raised to 220°C over a 1-hr period, kept there for 3 hr to ensure complete removal of acetic acid, and then cooled. The distillation is continued under reduced pressure to afford 86-95 gm (80-87%), b.p. 109- 112°C (3 mm Hg) and b.p. 118-121°C (6 mm Hg). |
|
Flammability and Explosibility |
Notclassified |
InChI:InChI=1/C12H22O3/c1-3-5-7-9-11(13)15-12(14)10-8-6-4-2/h3-10H2,1-2H3
2051-49-2 Relevant articles
A Semisynthetic Approach to New Immunoadjuvant Candidates: Site-Selective Chemical Manipulation of Escherichia coli Monophosphoryl Lipid A
D'Alonzo, Daniele,Cipolletti, Manuela,Tarantino, Giulia,Ziaco, Marcello,Pieretti, Giuseppina,Iadonisi, Alfonso,Palumbo, Giovanni,Alfano, Alberto,Giuliano, Mariateresa,De Rosa, Mario,Schiraldi, Chiara,Cammarota, Marcella,Parrilli, Michelangelo,Bedini, Emiliano,Corsaro, Maria M.
, p. 11053 - 11063 (2016)
A semisynthetic approach to novel lipid ...
Ketonization of hexanoic acid to diesel-blendable 6-undecanone on the stable zirconia aerogel catalyst
Lee, Yunsu,Choi, Jae-Wook,Suh, Dong Jin,Ha, Jeong-Myeong,Lee, Chang-Ha
, p. 288 - 293 (2015)
The ketonization of hexanoic acid, which...
One-pot electrochemical synthesis of acid anhydrides from alcohols
Kashparova,Papina,Kashparov,Zhukova, I. Yu.,Ilchibaeva,Kagan, E. Sh.
, p. 2733 - 2735 (2017/12/26)
One-pot indirect electrochemical oxidati...
Zinc(0)/dimethylformamide-mediated synthesis of symmetrical carboxylic anhydrides from acid chlorides
Serieys, Audrey,Botuha, Candice,Chemla, Fabrice,Ferreira, Franck,Pérez-Luna, Alejandro
, p. 5322 - 5323 (2008/12/22)
The high yielding synthesis of symmetric...
2051-49-2 Process route
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450408-65-8
4,5-dichloro-2-hexanoyl-2H -pyridazin-3-one
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932-22-9
4,5-dichloro-2H-pyridazin-3-one
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2051-49-2
n-hexanoic anhydride
| Conditions | Yield |
|---|---|
|
With
zinc(II) chloride;
In
acetonitrile;
for 6h;
Heating;
|
91%
|
-
-
111-27-3
hexan-1-ol
-
-
6378-65-0
n-hexyl caproate
-
-
2051-49-2
n-hexanoic anhydride
-
-
66-25-1
hexanal
| Conditions | Yield |
|---|---|
|
With
2,6-dimethylpyridine; 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; sodium hydrogencarbonate; potassium iodide;
In
dichloromethane; water;
pH=8.6;
Electrolysis;
|
25.5 %Chromat.
5.9 %Chromat. 66.1 %Chromat. |
2051-49-2 Upstream products
-
92351-84-3
acetic acid hexanoic acid-anhydride
-
108-24-7
acetic anhydride
-
142-62-1
hexanoic acid
-
463-51-4
Ketene
2051-49-2 Downstream products
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39556-41-7
hexanoic acid-(2-hydroxy-propyl ester)
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67032-31-9
3,5-bis-hexanoylamino-2,4,6-triiodo-benzoic acid
-
19817-88-0
2-hexanoylamino-2-deoxy-D-glucose
-
10312-45-5
17β-hexanoyloxy-androst-4-en-3-one
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