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HEXANOIC ANHYDRIDE

  • CAS No.: 2051-49-2
  • Purity: 99%
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Factory Sells Best Quality HEXANOIC ANHYDRIDE 2051-49-2 with stock

  • Molecular Formula: C12H22O3
  • Molecular Weight: 214.305
  • Appearance/Colour: clear colorless to light yellow liquid 
  • Vapor Pressure: 0.0263mmHg at 25°C 
  • Melting Point: -40 °C 
  • Refractive Index: n20/D 1.428(lit.)  
  • Boiling Point: 246.999 °C at 760 mmHg 
  • Flash Point: 116.614 °C 
  • PSA: 43.37000 
  • Density: 0.943 g/cm3 
  • LogP: 3.21680 

HEXANOIC ANHYDRIDE(Cas 2051-49-2) Usage

Preparation

To an ice-cooled flask containing 116 gm (1.0 mole) of n-caproic acid is added 21.0-23.10 gm (0.5-0.55 mole) of ketene at a rate of 0.45 mole/hr. The reaction mixture is fractionally distilled at atmospheric pressure to afford a forecut of acetone, acetic acid, and acetic anhydride. The oil bath is raised to 220°C over a 1-hr period, kept there for 3 hr to ensure complete removal of acetic acid, and then cooled. The distillation is continued under reduced pressure to afford 86-95 gm (80-87%), b.p. 109- 112°C (3 mm Hg) and b.p. 118-121°C (6 mm Hg).

Flammability and Explosibility

Notclassified

InChI:InChI=1/C12H22O3/c1-3-5-7-9-11(13)15-12(14)10-8-6-4-2/h3-10H2,1-2H3

2051-49-2 Relevant articles

A Semisynthetic Approach to New Immunoadjuvant Candidates: Site-Selective Chemical Manipulation of Escherichia coli Monophosphoryl Lipid A

D'Alonzo, Daniele,Cipolletti, Manuela,Tarantino, Giulia,Ziaco, Marcello,Pieretti, Giuseppina,Iadonisi, Alfonso,Palumbo, Giovanni,Alfano, Alberto,Giuliano, Mariateresa,De Rosa, Mario,Schiraldi, Chiara,Cammarota, Marcella,Parrilli, Michelangelo,Bedini, Emiliano,Corsaro, Maria M.

, p. 11053 - 11063 (2016)

A semisynthetic approach to novel lipid ...

Ketonization of hexanoic acid to diesel-blendable 6-undecanone on the stable zirconia aerogel catalyst

Lee, Yunsu,Choi, Jae-Wook,Suh, Dong Jin,Ha, Jeong-Myeong,Lee, Chang-Ha

, p. 288 - 293 (2015)

The ketonization of hexanoic acid, which...

One-pot electrochemical synthesis of acid anhydrides from alcohols

Kashparova,Papina,Kashparov,Zhukova, I. Yu.,Ilchibaeva,Kagan, E. Sh.

, p. 2733 - 2735 (2017/12/26)

One-pot indirect electrochemical oxidati...

Zinc(0)/dimethylformamide-mediated synthesis of symmetrical carboxylic anhydrides from acid chlorides

Serieys, Audrey,Botuha, Candice,Chemla, Fabrice,Ferreira, Franck,Pérez-Luna, Alejandro

, p. 5322 - 5323 (2008/12/22)

The high yielding synthesis of symmetric...

2051-49-2 Process route

4,5-dichloro-2-hexanoyl-2<i>H</i>-pyridazin-3-one
450408-65-8

4,5-dichloro-2-hexanoyl-2H -pyridazin-3-one

4,5-dichloro-2H-pyridazin-3-one
932-22-9

4,5-dichloro-2H-pyridazin-3-one

n-hexanoic anhydride
2051-49-2

n-hexanoic anhydride

Conditions
Conditions Yield
With zinc(II) chloride; In acetonitrile; for 6h; Heating;
91%
hexan-1-ol
111-27-3

hexan-1-ol

n-hexyl caproate
6378-65-0

n-hexyl caproate

n-hexanoic anhydride
2051-49-2

n-hexanoic anhydride

hexanal
66-25-1

hexanal

Conditions
Conditions Yield
With 2,6-dimethylpyridine; 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy; sodium hydrogencarbonate; potassium iodide; In dichloromethane; water; pH=8.6; Electrolysis;
25.5 %Chromat.
5.9 %Chromat.
66.1 %Chromat.

2051-49-2 Upstream products

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